Takasago’s ligand and catalyst technologies are based on continuous efforts and numerous experiences over a quarter century. Please feel free to access our tehcnologies as well as products! We hope the following documents will help you achieve your chemistry.
Technical Documents
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Technical Information
- Index
- 1. Asymmetric Hydrogenation
- 1.1 Classical Hydrogenation
- 1.1.1 Functionalized ketones
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a. β-Ketoesters
b. α-Ketoesters
c. γ-Ketoesters
d. Hydroxyacetones & Amino ketones
e. 1.3-Diketones
f. Keto sufonates & Keto phosphonates
g. Dynamic Kinetic Resolution
- 1.1.2 Imines
- 1.1.3 Olefins
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a. α,β-Uunsaturated Carboxylic Acids
b. Itaconic acid delivatives
c. Allyl alcohols
d. α,β-Unsaturated lactones
e. Diketene & Methylene-γ-butyrolactone
f. Dehydro amino acids
g. Enamides h. Enamino esters
- 1.2 Direct Reductive Amination
- 1.3 RuCl2(diphosphine)(diamine) catalyzed Hydrogenation
-
a. Aryl alkyl ketones & Heteroaryl alkyl ketones
b. Aryl aryl ketones
c. Others
d. Dynamic Kinetic Resolution
- 2. Asymmetric Isomerization
- 3. Monophosphine Ligands for Pd catalyzed Coupling Reactions
- 3.2 Suzuki-Miyaura Reaction
- 4. Other Reactions
- 4.1 Cyanomethylation
- 4.2 Vinylation & Phenylation
- 4.3 Fluorination
- 4.4 Aza-Michael addition
- 4.5 Asymmetric alcoholysis of azlactone
- 4.6 Cyclotrimerization of terminal alkynes
- 5. Publications
Ligand and Catalyst Guide
- Takasago Catalyst - Decision Tree-
- Ketone to Alcohol
- Ketone to Amine
- Olefin to Alkane
- Allylamine to Aldehyde
- Buchwald-Hartwig Reaction
- Suzuki-Miyaura Reaction
- Vinylation and Arylation
- Cyanomethylation
- Fluorination
- Hydrosilylation
General Procedure
- Procedure of Asymmetric Hydrogenation Using Diphosphine-Ruthenium Complex
- Procedure of Asymmetric Transfer Hydrogenation Using Ruthenium Complex
- Typical Procedure of Transesterification with ZnTAC24
- Typical Procedure of Hydrogenation Using Ru-MACHO
